Provas-N Tablet: Uses, Side Effects and Price in Pakistan

About Provas N Tablet

Provas-N tablet is a combination drug used as a muscle relaxant. It is a brand name of orphenadrine and paracetamol indicted in arthritis, migraine headaches, ear pain, back pain, etc. Provas-N or Provas forte also acts as an antipyretic due to the presence of paracetamol.

Consult a doctor to get a prescription for using the Provas N tablet.

Available Strengths of Provas N Tablet

Provas N tablet is available in the following strengths:

• Provas N Tablet 450/35mg
• Provas N Forte 650mg/50mg

Manufacturer: Sami Pharmaceuticals

Generic: Paracetamol 650 mg and Orphenadrine citrate 50 mg

Drug Class: Muscle relaxant, Analgesic, and Antipyretic

Product Form: Oral tablet (Provas N tablet, Provas N forte), Provas IV Injection 

Mechanism of Action

Provas N contains a combination of orphenadrine citrate, which acts as a muscle relaxant due to its anticholinergic effects. It binds to the NMDA receptors to reduce musculoskeletal pain.

Paracetamol is also present in Provas N, which acts centrally by reducing the synthesis of prostaglandins. Therefore, it acts as an analgesic and antipyretic.

What are the Uses of the Provas-N Tablet?

Some of the major uses of Provas N tablet include:

• Muscle Pain: Provas N tablet is prescribed to manage musculoskeletal pain due to injuries, strains, and overuse of the muscles. The anti-inflammatory and analgesic properties of the medicine help reduce the discomfort. 
• Muscle Spasm: The prescription use of Provas N tablet often relieves muscle spasms. It helps reduce the pain associated with the spasm due to muscle fatigue, dehydration, or certain medical conditions. The medicine relaxes the muscle fibers and reduces the intensity of the pain.
• Migraine Headache: Provas N tablet is a part of the comprehensive treatment plan to manage migraine pain. It reduces pain due to its analgesic properties and helps resolve other symptoms, including throbbing pain, often accompanied by nausea, vomiting, and sensitivity to light and sound.
• Pain Relief: Provas N tablet is a painkiller medication used to treat various types of pain, including ear pain, neck pain, back pain, and shoulder pain. It also provides an antipyretic effect by reducing the fever caused by these pains. 
• Post-Vaccine Pain: Vaccinations can sometimes lead to soreness or pain at the injection site. Some individuals might also experience body aches or mild fever post-vaccination. Provas N tablet can be prescribed to manage these symptoms, ensuring minimal discomfort after vaccination.

What is the Price of the Provas N Tablet in Pakistan?

The price of Provas N tablet in Pakistan ranges between 8-9 PKR per tablet. The exact cost can vary depending on the manufacturer. 

Alternatives of Provas-N tablet?

The available alternatives for Provas N tablet include:

• Norflex
• Norgesic
• Sinaxamol

How to Take Provas N Tablet?

To use Provas N tablet:

• Swallow the medicine as a whole with water.
• Take the medicine at the same dose and time as the doctor prescribes. 
• Do not increase the dose of the medicine on your own.
• Try to take the medicine simultaneously each day to make its effect optimal.
• If you are using an extended-release Provas N tablet, it is strictly recommended not to break the tablet before use.

Dosage of Provas N Tablet

You should follow the dosing regime prescribed by the doctor for your medical condition.

• The usual dose of Provas N tablet is 2 tablets three times a day.
• Follow the dosage of Provas N Forte as recommended by the doctor.
• Do not exceed the recommended dose to avoid possible side effects.

What are the Side Effects of the Provas N tablet?

The side effects reported with the use of Provas N tablet include:

• Lightheadedness
• Nausea and vomiting
• Hallucinations
• Anxiety
• Allergic reactions
• Dry mouth
• Trouble urinating
• Fainting

If any of these side effects persist, report them immediately to the doctor. 

Interactions of Provas N Tablet with Other Medicines

It is important to inform the doctor about all the pharmacological or herbal medicines that you are taking. This ensures the medicine’s safety and helps avoid drug interactions.

Some of the drugs that can interact with other medicines include;

• CNS antidepressants
• Warfarin
• Anticholinergics
• Antihistamines
• Phenothiazines
• Alcohol

Warnings and Precautions Associated with Provas-N Tablet

Take care of the following precautions and contraindications while using Provas tablet:

• The medicine is not recommended for people who have hypersensitivity to any of the contents of the medicine.
• Provas N is to be adjusted in patients with kidney disease as the major part of the medicine is secreted via the renal route. Kidney damage can slow down the elimination of the drug
• Dosage adjustments and continuous monitoring are required in patients with liver failure.
• Provas N can worsen the symptoms of patients suffering from myasthenia gravis therefore avoid using the medicine in such patients.
• Discontinue the use of Provas if the side effects get worse.

Is It Safe to Use Provas-N Tablet During Pregnancy?

The safety of Provas N tablet in pregnancy is not fully established. It can impart harmful effects on the developing fetus and mother. Similarly, insufficient research indicates this medicine’s use in breastfeeding.

It is recommended to consult your doctor before using Provas tablet during pregnancy or lactation to avoid any complications. 

What are the Effects of a Provas-N Tablet Overdose?

An overdose of Porvas N tablets can cause breathing difficulties. Other symptoms of overdose include:

• Fainting
• Seizures
• Irregular Heartbeat

Report immediately to the emergency in case of an accidental drug overdose. 

Missed Dose

Following the prescribed dosage of Provas N or Provas forte tablet is recommended. If you miss the dose, take it as soon as you remember. If the time of the next dose is near, skip the previous missed dose and take the upcoming dose as per the dosing schedule.

How to Store Provas N Tablet?

Follow these general instructions to store Provas N tablet:

• Store the medicine in a cool, dry place.
• Keep the medicine out of the reach of children.
• Store the medicine away from moisture and direct sunlight.

FAQs

1. Is orphenadrine a painkiller?

Orphenadrine is a muscular relaxant that is used as a painkiller during arthritis, and sprains. The medicine belongs to the class of analgesics due to paracetamol in it.

2. Is orphenadrine safe?

The safety profile of orphenadrine for long-term treatment is not fully established. It is commonly included in the short-term treatment plan for muscular diseases.