Metodine DF Suspension belongs to the class of antibiotics and is used for treating bacterial and protozoal infections. Metodine is prescribed for treating diarrhea, dysentery, and other related gastrointestinal infections. It is an FDA-approved medicine and is considered safe in pregnancy if the benefits outweigh the risks.
Manufactured by: Searle Pakistan Limited
Generic: Metronidazole & Diloxanide Furoate
Drug Class: Antiprotozoal
Product form: Suspension
Book a consultation with the doctor to get a prescription for Metodine suspension.
Mechanism of action
Metronidazole is an antibiotic that works by killing the bacteria. It damages the DNA of the organisms, resulting in the death of the microbes. Diloxanide is an amoebicide that works in the large intestine and kills the causative parasites. The combination works to treat amoebic and parasitic infections but is not active against viral infections.
What is the Metodine suspension price in Pakistan?
Metodine DF suspension price in Pakistan ranges between 100-120 PKR for 60 ml. The price can vary depending on the manufacturer and the pack size.
What are Metodine DF suspension uses?
Metodine DF suspension is used to treat the following microbial infections;
Treatment for Hepatic Amoebiasis: Metodine containing an antiamoebic combination effectively treats amoebic liver abscess, a complication of intestinal amoebiasis. Metodine also efficiently combats dysentery and diarrhea resulting from these organisms.
Giardiasis: Metodine is also used in treating infections caused by the protozoan parasite Giardia lamblia and alleviates associated bloating, loose motion, diarrhea, and abdominal cramps.
Eradication of Asymptomatic Amoebiasis: Metodine DF suspension is also prescribed for infections caused by E. histolytica. It effectively restricts the parasitic transmission to the other parts of the body.
Management of Trichomoniasis: Metronidazole finds its use in treating trichomoniasis, a parasite-induced sexually transmitted infection.
How to take Metodine Suspension?
The general instructions linked with the use of Metodine syrup include the following;
- Before using the suspension, shake the bottle well to ensure the medication is evenly distributed.
- Use a measuring spoon to measure the exact prescribed dose of the medicine. The use of household spoons may not provide the intended dosage.
- Generally, the medicine is taken 30 minutes before meals and at bedtime.
- Avoid discontinuing the medicine on your own, even if the symptoms subside. This is because the incomplete course of antibiotics may cause a recurrence of the infection.
- Follow the prescription strictly to avoid any complications.
What is Metodine dosage?
The usual prescribed dose of the suspension is;
For children under 4 yrs: 5 ml of the 60ml suspension three times a day
For children >5 years: 10ml of the 60ml suspension thrice daily.
For adults: As prescribed
What are Metodine side effects?
A few of the side effects caused by the medicine include;
- Headache
- Dry mouth
- Nausea
- Diarrhea
- Metallic taste in the mouth
- Dark urine
- CNS disturbances
- Neuropathy
- Seizures
- Unusual bleeding or bruising
- Skin rash or itching
- Fever or other signs of infection
Serious side effects can include:
- Tardive dyskinesia
- Neuroleptic malignant syndrome
- Hypotension
- Bradycardia
What are the warnings associated with Metodine Syrup?
A few of the risks and warnings associated with Metodine suspension are;
- Avoid using the medicine on patients suffering from liver or kidney diseases.
- Patients suffering from colitis and irregular heart rhythm must observe caution and use Metodine syrup only on prescription.
- Report immediately to the doctor if extreme dehydration, dry mouth, and no urination are experienced.
- Prolonged use of Metodine is associated with leukopenia, which is a low white blood cell count.
- Plenty of fluid intake is recommended to avoid dehydration and excessive fluid loss if you suffer from diarrhea or dysentery.
- Discontinue using the syrup and report immediately to the doctor if you have an allergic reaction to Metodine.
- In some people, the medicine may cause dizziness. Therefore, be careful while driving or swimming when on Metodine.
- Avoid eating spicy or unhygienic foods to increase the therapeutic effect of the medicine.
- Inform the doctor about all the prescription and non-prescription medicines you take to avoid drug interactions.
Does Metodine react with other medicines?
Metodine may cause drug-drug interactions with a variety of medicines, including;
- Busulfan
- Cimetidine
- Phenobarbital
- Warfarin
- Lithium
Is Metodine safe during pregnancy?
Metodine containing metronidazole is characterized under pregnancy category B. The medicine has shown no side effects in animal studies, but little data on its effects on pregnant women is available.
Traces of the medicine is reported in breast milk; therefore, use it only when its benefits outweigh the harmful effects in lactating women.
Consult a gynecologist before using Metodine during pregnancy and breastfeeding.
What are the alternatives for Metodine?
The alternative brands for Metodine include;
- Flagyl
- Entamizole
- Diprotop-MD
- Dizet
How to store Metodine Suspension?
The general storage instructions of the suspension include the following;
- Store the medicine out of the reach of children.
- Keep the medicine away from direct sunlight.
- Store the syrup in a tightly closed container, away from moisture.
Consult a doctor now to know more about the Metodine suspension
FAQs
1. What type of antiemetic is metachlopramide?
Metoclopramide is an FDA-approved D2 receptor antagonist. This prokinetic antiemetic drug treats nausea, vomiting, or loss of appetite.
2. Is Metodine safe in 5 weeks pregnant?
Metodine is considered a safe option to take during pregnancy. No harm to the baby or the mother is reported. However, consulting a gynecologist is recommended before taking Metodine during early pregnancy.
3. Can Metodine stop loose motion?
Metodine can be used against diarrhea and dysentery to stop loose motion caused by amoeba or other parasites. It is important to consult a doctor before using the antibiotic.
Disclaimer: The content was published on Marham. pk is for informational or educational purposes only, produced from FDA-approved literature, and does not substitute professional medical advice. Please consult your healthcare provider before using a prescription or over-the-counter drug or any other treatment option.