Hydrozole Cream: Uses, Side Effects, and Price in Pakistan

Hydrozole cream is an FDA-approved topical medication used for treating fungal infections such as ringworm, and seborrheic dermatitis. It contains two active ingredients, clotrimazole, and hydrocortisone, which help treat skin infections and soothe skin irritation. 

Manufactured by: GSK Consumer Healthcare

Generic: Clotrimazole and Hydrocortisone

Drug Class: Antifungal agents

Product form: Topical cream

Mechanism of Action of Clotrimazole 

Clotrimazole is an antifungal medication that inhibits the synthesis of ergosterol, a key component of fungal cell membranes. This disruption of the cell membrane structure leads to leakage of cellular contents and, ultimately, fungal cell death. Clotrimazole is commonly used to treat fungal infections, including athlete’s foot, jock itch, and ringworm.

Available Strength

Hydrozole cream 20g

What is the Hydrozole Cream price in Pakistan?

Hydrozole cream 20g price in Pakistan ranges between 210-220 PKR, but this price varies depending on the manufacturer.

What is Hydrozole Cream used for?

Hydrazone antifungal cream is used for;

• Fungal infections: Hydrozole contains two active ingredients, hydrocortisone, and clotrimazole, which work together to treat fungal infections of the skin, such as athlete’s foot, ringworm, and jock itch.
• Skin inflammation or itching: Hydrocortisone used in this cream is a corticosteroid, which helps reduce inflammation and itching associated with skin conditions such as eczema, dermatitis, and psoriasis.
• Seborrheic dermatitis: This cream can also be used to treat the symptoms of seborrheic dermatitis, such as red, scaly patches on the skin, particularly on the scalp and face. The clotrimazole in this cream helps to control the yeast that can contribute to seborrheic dermatitis, while the hydrocortisone helps to reduce inflammation and itching.
• Insect bites and stings: Hydrozole is used to soothe the itching and inflammation associated with insect bites and stings. Hydrocortisone in this cream reduces inflammation and itching, while the clotrimazole component can help prevent secondary bacterial or fungal infections.
• Nappy rash: Hydrozole cream can be used to reduce nappy rash in infants, as hydrocortisone in the cream has a calming impact on the rash, facilitating longer periods of sleep for the baby.

How to use Hydrozole Cream?

Use this cream by following these recommendations:

• Wash and dry the affected area thoroughly before applying the cream.
• Squeeze a small amount of cream onto your fingertip and apply a thin layer to the affected area.
• Gently rub the cream into the skin until it disappears.
• Repeat the application of the cream twice or thrice a day or as directed by your healthcare provider.
• Wash your hands after applying the cream unless you treat your hands.

What is Hydrozole dosage?

The dosage of this cream depends on the type of fungal skin infection under treatment, as well as the severity of the infection. However, the following are general guidelines for this cream dosage:

• For athlete’s foot: Apply this cream to the affected area twice daily for 2-4 weeks.
• For jock itch: Apply a thin layer of this cream to the affected area 2 times daily for two to four weeks.
• For ringworm: Use the cream on the affected area twice daily for two to four weeks.

What are Hydrozole side effects?

This cream may cause side effects, including:

• Burning or stinging sensation
• Itching or irritation at the site of application
• Dry skin
• Skin redness or rash

Less commonly, this cream may cause more severe side effects, such as:

• Allergic reactions, including hives, swelling of the face, lips, tongue, or throat, and difficulty breathing
• Skin discoloration or thinning 
• Acne or excessive hair growth
• Worsening of the underlying condition
• Skin infection or other skin conditions

If you experience any of these side effects or other unusual symptoms while using this cream, stop using the medication and seek medical attention immediately.

What are the warnings associated with Hydrozole cream?

Beware of these warnings before using this cream:

• Do not use Hydrocortisone cream on broken or infected skin, as it can increase the risk of systemic absorption and the development of side effects.
• Do not use this cream on the face or underarms, as it may cause skin thinning and other adverse effects.
• Hydrocortisone cream is for external use and should not be ingested or applied to the eyes, mouth, or mucous membranes.
• Do not use Hydrozole if allergic to its ingredients or other topical antifungal medications.
• If you have a history of liver disease or are taking medications that may affect liver function, consult your healthcare provider before using this cream.
• If symptoms of skin infection do not improve within two weeks of using this cream, or if they worsen or recur, stop using the cream and consult a dermatologist at your earliest possible.

Must read: Best Acne Cream in Pakistan with Price (Effective Skin Products)

Does Hydrozole react with medicines?

Hydrocortisone cream can potentially interfere with the following:

• Warfarin
• Cyclosporine
• Phenytoin
• Rifampicin
• Protease inhibitors

Is Hydrozole cream safe during Pregnancy?

This cream contains two active ingredients, hydrocortisone and clotrimazole; both are considered safe during pregnancy and lactation. However, it’s always better to consult a gynecologist before using any medication during pregnancy and lactation. 

What are the alternatives to Hydrozole Cream?

The alternatives for this cream are;

• Clotrimazole cream
• Miconazole cream
• Lamisil cream
• Ketoconazole cream

What happens with Hydrozole overuse?

Overuse of this cream can lead to:

• Increased risk of infection
• Striae or stretch marks, acne, and excessive hair growth. 
• Prolonged use may also result in systemic effects such as adrenal suppression and Cushing’s syndrome. 

It’s important to use this cream only as directed by a dermatologist and to follow the recommended treatment duration.

What happens if you miss the Hydrozole dose?

If you miss a dose of this cream, apply it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to compensate for the missed one, as this can increase the risk of side effects. 

How to store Hydrozole Cream?

Follow these instructions for storing your cream:

• Store the cream at room temperature, away from moisture and heat. 
• Keep the cream tightly closed in its original container when not in use. 
• Keep it out of reach of children and pets. 
• Check the expiry date before using the cream, and discard it if it has expired, appears discolored, or has an unusual odor.

FAQs

1. Is Hydrozole cream safe for babies?

While Hydrozole may be considered safe for treating nappy rash in babies under 2 years of age, it’s important to seek guidance from a healthcare provider before use.

2. Is Hydrozole used for tinea?

Hydrozole treats fungal infections such as tinea, seborrheic dermatitis, and insect bites. People suffering from tinea should use it twice daily.