Aminophylline is a medication that consists of theophylline. It is a bronchodilator and helps to relax smooth muscles. It is used for the treatment of breathing conditions like bronchospasm and asthma.
Manufactured by: Hubei Meibao Pharmaceuticals Co. Ltd
Generic: Theophylline
Drug Class: Bronchodilators
Product form: Injection, Syrup, Tablet
Mechanism of Action
Aminophylline acts as a bronchodilator and a respiratory stimulant. Its component, theophylline, relaxes the smooth muscles. This works inside the air pathways and helps enhance the airflow. Additionally, it stimulates the breathing center in the mind, leading to extended respiration pressure and better airflow.
Available Strengths
- Aminophylline IV 25 mg/ml
- Aminophylline IV 250 mg/ml
How much does it cost?
The cost of Aminophylline 250mg injection ranges between 450 – 500 PKR. However, the price is subject to changes based on the local vendor’s discretion.
Primary Uses of Aminophylline
The following are the primary uses of aminophylline:
- Asthma: Aminophylline is used in the management of bronchial asthma. It relaxes muscle tissues inside the air passages and improves breathing.
- Chronic Obstructive Pulmonary Disorder (COPD): It is also used in the treatment of COPD by alleviating bronchospasm and improving lung function in COPD patients.
- Chronic Bronchitis: It is prescribed to individuals with persistent bronchitis. By relaxing the smooth muscle groups in the airways, it could lessen signs including coughing, wheezing, and shortness of breath.
- Neonatal Apnea: Aminophylline is used to treat apnea of prematurity. It stimulates the respiration centers inside the brain and regulates respiration patterns in such infants.
Ingestion Tips
When taking Aminophylline intravenously (IV), follow these general instructions:
- A healthcare professional administers Aminophylline IV.
- The medication is injected into a vein using a small catheter.
- The infusion rate is determined based on your specific condition.
- The infusion takes 30 minutes to 2 hours.
- During the infusion, you are monitored for any expected adverse reaction.
- It is important to remain still and follow any additional instructions provided by the healthcare professional during the administration.
- Inform your healthcare provider if you experience any unexpected or concerning symptoms during or after the IV infusion.
Ideal Dosage
The general dosage guideline for Aminophylline IV is:
- 5.7 mg aminophylline/kg (ideal body weight) intravenously over 30 minutes
Expected Side Effects
Here are some side effects of Aminophylline:
- Nausea and vomiting
- Headache
- Rapid or irregular heartbeat
- Restlessness or irritability
- Insomnia or difficulty sleeping
- Stomach discomfort or abdominal pain
- Increased urination
- Tremors or muscle twitching
- Flushing or redness of the skin
Consult a doctor right away if you experience any of these side effects.
Associated Risks
The precautions and warnings associated with aminophylline include;
- Risk of overdose due to narrow therapeutic range
- Potential for drug interactions with other medications
- Adverse cardiovascular effects such as arrhythmias
- Gastrointestinal disturbances like nausea and vomiting
- Possible hypersensitivity reactions like anaphylaxis
Do Not Use in Combination with:
- Erythromycin
- Ciprofloxacin
- Clarithromycin
- Fluvoxamine
- Propranolol
- Cimetidine
Alternatives to Aminophylline are:
- Albuterol
- Formoterol
- Fluticasone
- Budesonide
- Tiotropium bromide
- Prednisone
Storage Tips
Here are some guidelines for storing aminophylline IV:
- Store aminophylline IV in a cool, dry place.
- Protect it from direct sunlight.
- Keep it away from children.
- Follow any specific storage instructions provided by the manufacturer or healthcare professional.
- Do not use the medication if it has expired or shows signs of deterioration.
- Properly dispose of any unused or expired aminophylline IV according to local guidelines and regulations.
Consult an expert if you have any additional queries regarding taking aminophylline.
Disclaimer: The content published on Marham.pk is for informational or educational purposes only, produced from FDA-approved literature, and does not substitute professional medical advice. Please consult your healthcare provider before using a prescription or over-the-counter drug, or any other treatment option.
Disclaimer: The content published on Marham.pk is for informational or educational purposes only, produced from FDA-approved literature, and does not substitute professional medical advice. Please consult your healthcare provider before using a prescription or over-the-counter drug, or any other treatment option.