Angised Tablet: Uses, Side Effects, and Price in Pakistan

Angised tablet is a medication that contains glyceryl trinitrate as the active ingredient. It is commonly used for the treatment and prevention of angina and to control hypertension during cardiac surgery.

Manufactured by: GSK
Generic: Glyceryl Trinitrate
Drug Class: Vasodilator medicine
Product form: Oral, sublingual, buccal Tablets

Mechanism of Action

Angised tablet works by releasing nitric oxide, which causes relaxation of the smooth muscles in the blood vessels, leading to vasodilation and increased blood flow to the heart. This reduces the workload on the heart and helps to relieve the symptoms of angina.

Available Strengths

• Angised tablet 0.5 mg

What is the Angised tablet Price in Pakistan?

Angised 0.5 mg tablet price in Pakistan ranges between 8 – 10 PKR per tablet. The tablet price varies depending on the strength and manufacturer.

What is the Angised tablet used for?

It is commonly used for the following conditions:

• Angina: Angised tablet is used to treat and prevent angina by dilating the blood vessels and increasing blood flow to the heart muscle. It also helps to reduce the chest pain or discomfort associated with the condition.
• Hypertension during cardiac surgery: It is used to control hypertension during cardiac surgery.
• Perioperative myocardial ischemia: This tablet is also used to prevent perioperative myocardial ischemia, by dilating the blood vessels during or after surgery, which can reduce the risk of heart damage due to insufficient blood and oxygen supply.

It is important to note that Angised tablets should only be used as prescribed by a doctor, and should not be used to treat sudden, severe chest pain or as a substitute for emergency medical treatment.

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How to take the Angised tablet?

Follow these general instructions for taking an Angised tablet;

• Angised Tablet is usually taken orally or sublingually, which means it is placed under the tongue.
• The tablet when placed under the tongue should be allowed to dissolve completely without chewing or swallowing.
• It is important not to eat or drink anything while the tablet is under the tongue, as this may affect the absorption of the medication.

What is Angised dosage?

Here are some general dosing guidelines for Angised tablets:

• The usual dose for adults is 0.5 mg of an Angised tablet placed under the tongue as needed for the relief of angina symptoms.
• The maximum dose per day should not exceed 3 tablets.
• The dose may be adjusted by your healthcare provider based on your individual response to the medication.
• It is important to follow the dosing instructions provided by your healthcare provider and not exceed the recommended dose.

If you have any questions or concerns about the dosing of Angised tablets, consult a doctor.

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What are Angised tablet side effects?

Here are some side effects of Angised tablets:

• Headache
• Dizziness
• Flushing
• Nausea
• Vomiting
• Weakness
• Sweating
• Rapid heartbeat
• Low blood pressure
• Fainting
• Allergic reactions

If you experience any of these serious side effects, seek medical attention immediately from a cardiologist.

What are the warnings associated with the Angised tablet?

The precautions and warnings associated with Angised use include;

• Angised tablet should not be used if you are allergic to glyceryl trinitrate or any other ingredients in the medication.
• Do not use Angised Tablet if you have severe anemia, increased pressure in the head, or have recently taken drugs for erectile dysfunction (such as sildenafil or vardenafil).
• This medicine may cause dizziness or lightheadedness, so avoid driving or operating heavy machinery until you know how the medication affects you.
• Angised tablet may cause low blood pressure, which can be dangerous in some people, especially those with certain medical conditions. Your healthcare provider may monitor your blood pressure while you are taking this medication.
• This tablet may cause headaches, which can sometimes be severe. If you experience severe or persistent headaches while taking this medication, contact your healthcare provider.

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Does an Angised tablet react with medicines?

Here are some medications that may interact with Angised tablets:

• Sildenafil
• Fluoxetine
• Phenytoin
• Rifampin

Is Angised Tablet Safe during Pregnancy?

Angised Tablet is not recommended for use during pregnancy unless it is clearly needed and the potential benefits outweigh the potential risks to the fetus.

The medication is classified as Pregnancy Category C by the US FDA, which means that animal studies have shown adverse effects on the fetus, but there are no adequate and well-controlled studies in pregnant women.

If you are pregnant or planning to become pregnant, talk to a gynecologist before taking Angised Tablet. Your doctor can help you weigh the potential benefits and risks of taking the medication during pregnancy and determine if it is the right choice for you.

What are the alternatives to the Angised tablet?

Some of the alternative brands for Angised tablets are;

• Isordil
• Imdur
• Nitrolingual
• Norvasc
• Cardizem
• Calan
• Lopressor
• Inderal

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What happens with an Angised tablet Overdose?

An overdose of Angised tablets can cause severe headaches, dizziness, lightheadedness, nausea, vomiting, rapid heartbeat, and low blood pressure.

In severe cases, it may lead to loss of consciousness or even death. If you suspect an overdose, seek emergency medical attention immediately.

What happens if you miss the Angised dose?

If you miss a dose of an Angised tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

How to store Angised tablets?

Here are some guidelines for storing Angised tablets:

• Store the medication at room temperature, away from heat, moisture, and direct light.
• Keep the tablets in their original container or packaging until ready to use.
• Do not store the tablets in the bathroom or other areas with high humidity or moisture.
• Keep the medication out of reach of children.
• Do not use the medication after the expiration date on the label.
• If you have any unused medication, dispose of it properly according to local guidelines or consult with a pharmacist.

If you have any further queries or concerns about taking Angised Tablet, it is recommended that you consult a cardiologist for guidance and advice.

FAQs

1. Which fruit is best for angina?

Antioxidants found in berries can aid in safeguarding your heart from oxidative stress and inflammation. Additionally, fruits such as citrus fruits, mangoes, and papayas are also considered beneficial for heart health.

2. Who should not take Angised?

People should not take an Angised tablet if they have an allergy to glyceryl trinitrate, nitroglycerin, or any of the ingredients present in the medication. It is also not recommended for individuals with anemia or those who have experienced head trauma or brain hemorrhage, which can lead to an increase in pressure within the brain.